Venkatasai is a leading innovator in the field of pharmaceutical reference standards, offering high-quality Reference Standards of Abemaciclib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope-labeled compounds, and nitrosamines (N-NO products). Our Abemaciclib impurity reference standards play a vital role in pharmaceutical research, supporting product development, ANDA and DMF filings, quality control (QC), method validation, and stability studies. They are also instrumental in identifying unknown impurities and evaluating genotoxic potential. All Abemaciclib-related products are thoroughly characterized and supplied with comprehensive Certificates of Analysis (COA) and analytical data that comply with regulatory standards. EP/USP traceable standards can also be provided upon request. Furthermore, all supplied products undergo periodic re-testing to ensure continued quality and reliability.
Abemaciclib
![N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119000.png)
Abemaciclib D10
![N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119008.png)
Abemaciclib D5
![?N-(5-((4-(Ethyl-d5)piperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119009.png)
Abemaciclib D7
![?N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-methyl-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119010.png)
Abemaciclib D8
![?N-(5-((4-Ethylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119007.png)
Abemaciclib Degradant Impurity-1
![6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-ol](watermark.php?img=VS-A119018.png)
Abemaciclib Degradant Impurity-2
![4-Ethyl-1-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methyl)piperazine 1-oxide](watermark.php?img=VS-A119014.png)
Abemaciclib Degradant Impurity-3
![(6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol](watermark.php?img=VS-A119013.png)
Abemaciclib Degradant Impurity-4
![6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)nicotinic acid](watermark.php?img=VS-A119017.png)
Abemaciclib Degradant Impurity-5
![6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)nicotinaldehyde](watermark.php?img=VS-A119012.png)
Abemaciclib Impurity 1
Abemaciclib Impurity 2
![6-(2-Chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole](watermark.php?img=VS-A119003.png)
Abemaciclib Impurity 3
Abemaciclib Impurity 4
![N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine](watermark.php?img=VS-A119005.png)
Abemaciclib Impurity 5
![4-Fluoro-6-(5-fluoropyrimidin-4-yl)-1-isopropyl-2-methyl-1H-benzo[d]imidazole](watermark.php?img=VS-A119006.png)
Abemaciclib Metabolites M2
![?5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine](watermark.php?img=VS-A119002.png)
Abemaciclib N-Oxide Impurity 2
![1-Ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methyl)piperazine 1-oxide](watermark.php?img=VS-A119015.png)
Abemaciclib N-Oxide Impurity 3
![5-((4-Ethylpiperazin-1-yl)methyl)-2-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridine 1-oxide](watermark.php?img=VS-A119016.png)
Abemaciclib Nitroso Impurity 1
![N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)nitrous amide](watermark.php?img=VS-A119011.png)
