Apalutamide

Apalutamide Related Products

Venkatasai is a leading innovator in the field of pharmaceutical reference standards, offering high-quality Reference Standards of Apalutamide, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope-labeled compounds, and nitrosamines (N-NO products). Our Apalutamide impurity reference standards play a vital role in pharmaceutical research, supporting product development, ANDA and DMF filings, quality control (QC), method validation, and stability studies. They are also instrumental in identifying unknown impurities and evaluating genotoxic potential. All Apalutamide-related products are thoroughly characterized and supplied with comprehensive Certificates of Analysis (COA) and analytical data that comply with regulatory standards. EP/USP traceable standards can also be provided upon request. Furthermore, all supplied products undergo periodic re-testing to ensure continued quality and reliability.

Apalutamide

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide
CAT No: VS-A073000
CAS No: 956104-40-8
Mol.F.: C21H15F4N5O2S
Mol.Wt.: 477.4
Status: Custom Synthesis

Apalutamide Acid

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid
CAT No: VS-A073003
CAS No: 1332391-04-4
Mol.F.: C20H12F4N4O3S
Mol.Wt.: 464.4
Status: Custom Synthesis

Apalutamide Acid sodium salt

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoic acid, sodium salt (1:1)
CAT No: VS-A073009
CAS No: N/A
Mol.F.: C20H11F4N4O3S : Na
Mol.Wt.: 463.4 : 23.0
Status: Custom Synthesis

Apalutamide Amide impurity

5-(5-(3-fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinamide
CAT No: VS-A073011
CAS No: N/A
Mol.F.: C21H17F4N5O3S
Mol.Wt.: 495.5
Status: Custom Synthesis

Apalutamide Amine Impurity ( APA2 )

4-((1-cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide
CAT No: VS-A073007
CAS No: 915087-26-2
Mol.F.: C13H14FN3O
Mol.Wt.: 247.3
Status: Custom Synthesis

Apalutamide Desfluoro Impurity

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide
CAT No: VS-A073005
CAS No: 1332389-57-7
Mol.F.: C21H16F3N5O2S
Mol.Wt.: 459.4
Status: Custom Synthesis

Apalutamide Desmethyl Impurity

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide
CAT No: VS-A073006
CAS No: 1332391-11-3
Mol.F.: C20H13F4N5O2S
Mol.Wt.: 463.4
Status: Custom Synthesis

Apalutamide Dithio Impurity

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-Dithioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluoro-N-methylbenzamide
CAT No: VS-A073004
CAS No: N/A
Mol.F.: C21H15F4N5OS2
Mol.Wt.: 493.5
Status: Custom Synthesis

Apalutamide Dithio Impurity

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-Dithioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluoro-N-methylbenzamide
CAT No: VS-A073030
CAS No: 2649802-40-2
Mol.F.: C21H15F4N5OS2
Mol.Wt.: 493.5
Status: Custom Synthesis

Apalutamide Impurity 10 (Aminopyridine)

5-Amino-3-(trifluoromethyl)picolinonitrile
CAT No: VS-A073019
CAS No: 573762-62-6
Mol.F.: C7H4F3N3
Mol.Wt.: 187.1
Status: Custom Synthesis

Apalutamide Impurity 11

5-Nitro-3-(trifluoromethyl)picolinonitrile
CAT No: VS-A073020
CAS No: 573762-57-9
Mol.F.: C7H2F3N3O2
Mol.Wt.: 217.1
Status: Custom Synthesis

Apalutamide Impurity 12

5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one
CAT No: VS-A073021
CAS No: 99368-66-8
Mol.F.: C6H3F3N2O3
Mol.Wt.: 208.1
Status: Custom Synthesis

Apalutamide Impurity 13

2-Bromo-5-nitro-3-(trifluoromethyl)pyridine
CAT No: VS-A073022
CAS No: 956104-42-0
Mol.F.: C6H2BrF3N2O2
Mol.Wt.: 271
Status: Custom Synthesis

Apalutamide Impurity 14

4-Amino-N-methylbenzamide
CAT No: VS-A073023
CAS No: 6274-22-2
Mol.F.: C8H10N2O
Mol.Wt.: 150.2
Status: Custom Synthesis

Apalutamide Impurity 15

2-Fluoro-4-nitrobenzoic acid
CAT No: VS-A073024
CAS No: 403-24-7
Mol.F.: C7H4FNO4
Mol.Wt.: 185.1
Status: Custom Synthesis

Apalutamide Impurity 16

2-Fluoro-N-methyl-4-nitrobenzamide
CAT No: VS-A073025
CAS No: 915087-24-0
Mol.F.: C8H7FN2O3
Mol.Wt.: 198.2
Status: Custom Synthesis

Apalutamide Impurity 17

2-Fluoro-1-methyl-4-nitrobenzene
CAT No: VS-A073026
CAS No: 1427-07-2
Mol.F.: C7H6FNO2
Mol.Wt.: 155.1
Status: Custom Synthesis

Apalutamide Impurity 18

4-Amino-2-fluorobenzoic acid
CAT No: VS-A073027
CAS No: 446-31-1
Mol.F.: C7H6FNO2
Mol.Wt.: 155.1
Status: Custom Synthesis

Apalutamide Impurity 19

4-Amino-2-fluro-N-Methylbenzamide
CAT No: VS-A073029
CAS No: 915087-25-1
Mol.F.: C8H9FN2O
Mol.Wt.: 168.2
Status: Custom Synthesis

Apalutamide Impurity 20

3-(Trifluoromethyl)-2-pyridone
CAT No: VS-A073031
CAS No: 22245-83-6?
Mol.F.: C6H4F3NO
Mol.Wt.: ?163.10?
Status: Custom Synthesis

Apalutamide Impurity 3

4-((1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide
CAT No: VS-A073012
CAS No: 1950587-20-8
Mol.F.: C20H17F4N5O2
Mol.Wt.: 435.4
Status: Custom Synthesis

Apalutamide Impurity 4

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide
CAT No: VS-A073013
CAS No: N/A
Mol.F.: C29H21F5N6O3S
Mol.Wt.: 628.6
Status: Custom Synthesis

Apalutamide Impurity 5

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide
CAT No: VS-A073014
CAS No: N/A
Mol.F.: C40H27F8N9O4S
Mol.Wt.: 881.8
Status: Custom Synthesis

Apalutamide Impurity 6

O-phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate
CAT No: VS-A073015
CAS No: N/A
Mol.F.: C28H19F4N5O3S2
Mol.Wt.: 613.6
Status: Custom Synthesis

Apalutamide Impurity 7 ( APA2 Acid )

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid
CAT No: VS-A073016
CAS No: 2227589-22-0
Mol.F.: C13H15FN2O3
Mol.Wt.: 266.3
Status: Custom Synthesis

Apalutamide Impurity 7 (Potassium salt)

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid, potassium salt (1:1)
CAT No: VS-A073017
CAS No: 2408380-71-0
Mol.F.: C13H15FN2O3 : K
Mol.Wt.: 266.3 : 39.1
Status: Custom Synthesis

Apalutamide Impurity 8

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide
CAT No: VS-A073018
CAS No: N/A
Mol.F.: C8H9FN2O2
Mol.Wt.: 184.2
Status: Custom Synthesis

Apalutamide N-Oxide

2-Cyano-5-(5-(3-fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)pyridine 1-oxide
CAT No: VS-A073008
CAS No: N/A
Mol.F.: C21H15F4N5O3S
Mol.Wt.: 493.4
Status: Custom Synthesis

Apalutamide Oxamide

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)urea
CAT No: VS-A073001
CAS No: N/A
Mol.F.: C8H5F3N4O
Mol.Wt.: 230.2
Status: Custom Synthesis

Apalutamide Thioamide

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea
CAT No: VS-A073002
CAS No: 2422147-84-8
Mol.F.: C8H5F3N4S
Mol.Wt.: 246.2
Status: Custom Synthesis

6,8-Dioxo Apalutamide

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide
CAT No: VS-A073010
CAS No: 1332391-92-0
Mol.F.: C21H15F4N5O3
Mol.Wt.: 461.4
Status: Custom Synthesis

N-Nitroso Apalutamide Amine Impurity

4-((1-cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide
CAT No: VS-A073028
CAS No: N/A
Mol.F.: C13H13FN4O2
Mol.Wt.: 276.3
Status: Custom Synthesis

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